Random observations played a critical role in many of the greatest scientific discoveries. This refers especially to England. So, in 1928, Alexander Fleming accidentally discovered that some dirty mold (penicillin) destroyed almost all types of bacteria that Dr. Fleming grew in the cup.
And, of course, speaking of coincidences in science, one can not forget about Isaac Newton. He was lucky enough to sit underneath the tree just when apples are falling down- so the idea entered his mind that it is a good idea to study the laws of gravity. Viagra, perhaps, will be the third of the great “accidental” discoveries made by Englishman.
But unlike Newton’s discovery, Viagra in some way marks the victory over gravity: finally, a means was found, which cured «helplessly hanging penises»! Viagra history started in 1992 in England, Pfizer Sandwich, in the course of scientific investigations on instructions of Pfizer – pharmaceutical company.
The researchers conducted clinical trials of sildenafil citrate obtained in the laboratory, studying the possibility of using it to treat angina – a disease that manifests itself in the form of acute heart pain attacks when coronary arteries that feed heart muscle are narrowed because of atherosclerosis and spasmed. Scientists have calculated that sildenafil citrate will enhance blood flow to the cardiac muscle.
But research results have shown that sildenafil citrate does not significantly affect the coronary circulation and facilitates angina attacks in patients of the studied group. At the same time, it was found that male patients who participated in the study, did not want to return the remaining sildenafil pills, despite the end of testing. Here’s why: drug effect on the coronary blood flow was minimal, sildenafil caused significant blood flow to the male genitals provoking erection appearance! Canadian Pharmacy points out that this medication makes many men come back to sexual life.
Truly it was the most pleasant of all the possible side effects that can be only caused medicine! Employees of pharmaceutical companies paid due consideration to this property and sildenafil was able to recognize powerful means to combat erectile dysfunction. The new drug – generic Viagra – name coined for a long time and have been waiting for the moment.
In 1993, employees began long – lasting costly clinical trials needed to confirm definitively the fact that Viagra is really effective and safe treatment for erectile dysfunction.
Over the next 4 years, s the company has conducted twenty-one clinical trial of a new drug, during which its effect was tested by 4500 men suffering from erectile dysfunction. The total cost of research was estimated at 500 million. March 1998 saw that tests were successfully completed, Viagra was invented, it was allowed to be sold in the United States and other countries. Viagra has become the first oral medication providing men with an opportunity to treat erectile dysfunction and revive sexual life.
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