Sildenafil (Viagra) is the most effective treatment for ED but it records the highest rate of side effects. Men who are concerned about the possible side effects of Viagra such as flushing, headaches, nasal congestion, and indigestion might want to start off the treatment with Cialis. If that turns out to be ineffective, men in some countries might try out udenafil (Zydena).

Studies have found out that the treatment with these oral drugs are more effective than placebo and are usually safe and well-tolerated. Around 50-100mg of Viagra turned out to be the most effective. Smaller doses had less effect. A 50-200mg dose of Stendra was the least effective and about 30% more effective than placebo.

However, 50mg of Generic Stendra was reported to have the least side effects. On the other hand, 20mg of Levitra had around 25% side effect. High dose of Viagra and Cialis had side effects in between 21% to 22% of the time.

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According to Canadian Health&Care Mall, the side effects actually depend on the drug that is being used and the other enzymes that the drug is inhibiting. One of the main side effects of Viagra is the changes in the visualization, whereas Cialis can cause muscle pain in patients. ED drug can cause a sudden drop in the blood pressure.

Other common side effects of the oral drugs include:

  • facial flushing;
  • headache;
  • congestion;
  • upset stomach.

However, you have to option of trying out each of the drugs to find out which one works the best for you, except if you are using Cialis. This is because Cialis is to be taken on a regular basis. PDE-5 is taken to be the first choice to treat ED but it is effective only of (60-80) % of men.

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What Is Erectile Dysfunction?

Erectile dysfunction or impotence is referred to a condition when you are unable to get or keep an erection that this firm enough for having sexual intercourse. Occasional ED is not an uncommon phenomenon. Nonetheless, frequent ED can be a sign that you are having health problems.

Canadian Health&Pharmacy Mall mentions that you get an erection when there is an increased blood flow to the penis. When you get sexually excited the penis relaxes. This relaxation increases the blood flow to the arteries of the penis. The blood fills up the two chambers that are there in the penis which is known as the Corpora Cavernosa. The penis becomes rigid as the chambers get filled with blood. The penis becomes flaccid as the muscles start to contract and the blood that is accumulated in the penis flows out through the veins. Read more information relating to erectile dysfunction –

Symptoms of Erectile Dysfunction

  • inability to get an erection;
  • inability to retain erection till the entire length of sexual intercourse;
  • inability to attain an erection that is firm enough to penetrate the vagina.

Phosphodiesterase-5 Inhibitors

Treatment Options for Erectile Dysfunction

The treatment of erectile dysfunction depends on the cause.

Change in Lifestyle

ED can be improved if you make some changes in your lifestyle. These changes are:

  • losing weight;
  • cutting back on alcohol consumption;
  • abstaining from illegal drugs;
  • giving up smoking;
  • exercising regularly;
  • reducing stress.

Phosphodiesterase-5 Inhibitors

Phosphodiesterase-5 inhibitors are the most effectively used oral drug for ED. They temporarily increase the blood flow to the penis. The inhibitors that are available for ED are:

  • sildenafil;
  • vardenafil;
  • tadalafil;
  • avanafil.
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Depending on the type and the dose, it takes around 30 to t60 minutes to work. The effect lasts for a long time. It might take longer for the drug to work if you are taking it along with food.

Vacuum Pumps

A vacuum pump has a clear plastic tube that is linked to the pump. This is either battery or battery operated. It is placed inside the penis to pump out all the air. This leads to a vacuum that makes blood fill up the penis. After this, you place a rubber ring around the penis for keeping the blood in place which helps you to maintain an erection for around half an hour.Viagra, Cialis and Levitra


In the case, you are unwilling to use PDE-5 inhibitor, or unable to respond to the treatment of oral drugs, you can take alprostadil. It is available as:

  • an injection which is taken directly into the penis;
  • a small pellet which is placed inside the urethra.